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DEATH DOMAIN
Descriptors Found:
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DeCS
Descriptor
English
:
Death Domain
Descriptor
Spanish
:
dominio de muerte
Descriptor
Portuguese
:
Domínio de Morte
Synonyms
English
:
Death Domains
Tree Number:
G02.111.570.820.709.275.750.500.395.500
Definition
English
:
A conserved protein interaction domain of the
death domain superfamily
that is structurally
similar
to the
DEATH EFFECTOR DOMAIN
and CASPASE RECRUITMENT DOMAIN.
Death domains
bind each other to form oligomers and occur on
DEATH DOMAIN
RECEPTORS, where they are required for
APOPTOSIS
signaling and non-apoptotic functions.
History Note
English
:
2017
Allowable Qualifiers
English
:
DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
56747
Unique Identifier:
D000071459
Occurrence in VHL
:
Similar:
DeCS